Constant Temperature Humidity Chamber

The speed at which vaccines are being developed is unprecedented during the current coronavirus pandemic. Vaccines from companies such as Biontech and Pfizer are already on the market and will be available for vaccination as soon as possible. But how long is the shelf life of a new vaccine? This is exactly what major pharmaceutical companies need to test with Thchamber's constant temperature and humidity chambers today. Typically, it takes ten to twenty years to develop a vaccine. But with the ongoing coronavirus crisis, waiting this long is not a good option. With the number of infections and deaths at consistently high levels, calls for a rapid vaccine delivery are growing. Pharmaceutical companies are struggling to keep up with demand, but are also focusing on analyzing the stability of vaccines, which are developed in years and have to be adjusted based on how the virus mutates. This is where stability testing comes in, for example in the KBF or KBF LQC, a constant temperature and humidity chamber with ICH-compliant light and light control. Smart, safe, economical and reliable: this is Thchamber. One thing is for sure: Thchamber is your reliable partner during the COVID-19 pandemic. Why stress test the new crown vaccine? The goal of pharmaceutical companies is to demonstrate to the public that vaccines are still effective over extended periods of time or after being stored at different temperatures. It's too early to tell how well the various vaccines will work after changing conditions. Constant Temperature and Humidity Chamber: Stability Test of Novel Coronavirus Vaccine Test the effectiveness of the novel coronavirus vaccine using Thchamber's constant temperature and humidity chamber. For this type of test, experts attach great importance to the uniformity of the temperature distribution inside the constant temperature and humidity chamber. Thchamber drying ovens, ultra-low temperature freezers and mildew incubators can also support you during the pandemic. Drying Oven: especially suitable for the disinfection of masks According to the federal government, masks can be reused under certain preconditions. Place the mask in a drying oven at a temperature between 65 and 70 °C for 30 minutes. In this way, the virus can be inactivated. Low temperature refrigerator: can cool down to -25°C Virus samples, such as the new coronavirus, can also be stored in our low temperature freezers. Samples are stored securely in the box and are readily available for additional testing. Incubator: ideal for cell proliferation Large numbers of cells must be grown for the new coronavirus to be tested. Constant Temperature Humidity Chamber: Stability Test of Novel Coronavirus Vaccine Large pharmaceutical companies use Thchamber's constant temperature and humidity chambers around the world to test the effectiveness of the new coronavirus vaccine. For this type of test, experts attach great importance to the uniformity of the temperature distribution inside the constant temperature and humidity chamber.

In the pharmaceutical industry, stability testing helps demonstrate how drug quality changes over time under various environmental conditions, including temperature, humidity, and light. This testing must be done before the drug can reach the market. To test the quality of a drug at a specific temperature and humidity, a batch of the drug of interest is placed in a Constant Temperature Humidity Chamber for a specified period of time. Samples are checked periodically for quality analysis. Because stability testing can span anywhere from a week to six months to a year or more, the stability chambers used must be reliable and consistent. Another type of stability testing focuses on photostability, or how a drug is affected when exposed to certain amounts of light and ultraviolet light over time. For this type of testing, a stability chamber that meets specific guidelines and is capable of emitting the required light and UV light over time is required. Complying with ICH guidelines requires stability chamber with consistent performance Stability testing guidelines are outlined by the International Committee for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) and are followed by regulatory agencies worldwide, including the Food and Drug Administration (FDA), European Commission (EC), and Health Canada. Six ICH Guidelines (Q1A to Q1F) provide specific details for adequate testing. These guidelines are very specific, requiring that the temperature in the stabilization chamber not deviate by more than 2 or 3°C, depending on the conditions, and the humidity not deviate by more than 5%. Therefore, a stability chamber for such tests needs to have the low temperature and humidity excursions observed during prolonged testing. The temperature also needs to be uniform throughout the unit. Stabilization chambers that use traditional non-directional airflow systems use fans mounted on top of the unit to push air down through wire shelves. When racks are filled with samples, this air flow is blocked, causing changes in temperature conditions throughout the chamber. This inconsistency may affect stability conditions and overall stability testing. In contrast, a stabilization chamber that uses a horizontal laminar airflow system includes a positive-pressure feed chamber on one side of the chamber and a negative-pressure return chamber on the other side to create horizontal airflow directly across the surface of each shelf. Using this method means that even when the racks are full of samples, they receive a steady flow of conditioned air, resulting in optimal temperature uniformity throughout the chamber and across all samples. The horizontal laminar airflow system also increases the capacity of the stabilization chamber by ensuring temperature uniformity, even when the racks are full, enabling testing of larger sample batches. Reliable unit will maintain performance during long-term stability testing Samples can be tested in a stabilization chamber for a week, six months, a year or longer, depending on the type of testing performed. If one chamber fails, pharmaceutical labs could lose months of work and will be pushed backwards in their timelines, prolonging the time it takes for a drug to reach the market. Stability chambers used for stability testing in the pharmaceutical industry must be durable and rigorously tested for their long-term performance. Additional features help pharmaceutical labs feel safe when using the stability chamber. For example, high and low temperature alerts can warn users when temperatures deviate. Even better, remote monitoring systems allow users to keep track of what's going on in the room even when they're not in the lab. Requirements for Photostability Test Chamber Photostability testing evaluates whether drug products undergo unacceptable changes when exposed to a combination of white light and ultraviolet (UV) light. Stability chambers used for this type of testing need to provide ideal light emission to meet the ICH requirements of Guideline Q1B - they must be able to maintain more than 1.2 million lux hours of light and emit more than 200 watts of UV energy to the sample. Unlike stability testing for temperature and humidity, light stability testing can be completed in as little as a week, and specific units can be programmed to turn off the light when the desired exposure level is reached. One issue to consider when performing photostability testing is safety. Exposure to UV rays can cause damage to human eyes and should be avoided. A chamber with lights that automatically shut off when the door is opened will help prevent UV exposure and keep your workers safe. Other potential uses In the rare case that your pharmaceutical laboratory does not perform stability testing, the stability chamber can be used for other applications. For example, because they maintain a constant temperature and humidity, they are ideal containers for samples that need to maintain stablity conditions. Stability testing in the pharmaceutical industry is a time-intensive investment, and selecting the right instrument should not be taken lightly. Stability chambers for testing the stability of pharmaceuticals under different temperatures, humidity and light need to be reliable, stablity and comply with ICH guidelines.