Mold Incubator

Why Lab Refrigerator Temperature Alarms Are Crucial What could go wrong? Perhaps the first thing that comes to mind is a power failure. If your facility does not have emergency generators that come online immediately, you need a backup plan to quickly move production to a backup refrigeration system. Less likely, but not unknown, is a mechanical failure in the refrigeration system or a temperature excursion due to poor maintenance, such as icing on the evaporator coil. Another example is accidentally leaving the unit's door ajar. As a final example in this post, a temperature monitor that activates an alarm can fail. For whatever reason, personnel must be alerted if the temperature is above or below the set value. Quick response to temperature excursions helps protect contents from spoilage or loss of potency. Temperature alarm system To understand the alarm system, we first set up the stage. Temperature alarms are programmed by personnel based on the proper storage temperature of materials in freezers and refrigerators. Use a mechanical or digital thermostat to set the temperature. Temperature monitors consist of probes placed in refrigerators and freezers and connected to onboard or external display and control devices. Many of these come with battery backup to maintain functionality in the event of a power failure. For more information on temperature controls and monitors, see our post on the topic of vaccine storage. On-board alarm Examples of on-board systems include Nor-Lake Scientific laboratory freezers and refrigerators available from Tovatech. These feature digital LED microprocessor temperature controllers with high/low visual and audible temperature alarms and remote alarm contacts to alert personnel elsewhere in the facility. A temperature sensor is placed in the bottle filled with glycerin to better reflect the temperature of the contents than the ambient temperature in the unit. Such an arrangement also reduces the chance of triggering an alarm when the unit door is opened. Some models of Scientific Refrigeration systems provide power failure alarms and door ajar alarms. Auxiliary or optional alarm system General purpose laboratory refrigerators and freezers can be equipped with an optional digital thermometer alarm consisting of an internal probe housed in a glycerin-filled bottle that is wired to external control and alarm devices. Probably the best solution for notifying refrigeration failures is the iLab 600 temperature monitoring system from Tovatech. The device operates independently of the device by collecting data from an internal probe connected through an access port to an external pod, which in turn is connected to the facility's LAN. The iLab 600 has two functions: A sophisticated programmable high/low temperature alarm that sounds locally and sends email, text, phone or pager alerts to the personnel list during off hours. It also captures, remotely stores and instantly retrieves compliance data reports on laboratory freezer and laboratory refrigerator performance. An optional USB temperature data logger with built-in alarm can be used to automatically record internal temperature at user-programmable intervals using a NIST traceable probe. To read the results, simply plug the USB flash drive into the computer and transfer the data to the PC for viewing and archiving. In addition to the onboard and optional digital thermometer alarms, an iLab 600 or USB data logger is recommended for two reasons. First, you shouldn't rely on a single temperature sensor to drive a temperature warning system. There should be at least two completely separate monitoring systems with alarms linked to separate temperature sensors. Second, they provide a way to acquire, store and retrieve stored temperature data based on good laboratory and good manufacturing processes. Other Pharmaceutical Refrigerator Tips Despite sophisticated temperature monitoring and alarm systems, laboratory personnel have a responsibility to protect the contents of refrigerators and freezers from spoilage due to improper storage temperatures.   Be prepared for prolonged power outages. Large facilities should have a backup emergency power system to keep refrigerators and freezers functioning properly. Smaller labs can use portable generators. If they shouldn't have procedures in place to quickly move valuable specimens, vaccines and medicines to off-site locations. Keep in mind that full freezers and refrigerators will keep the temperature longer. Fill the empty space with an ice pack or water bottle. Minimize unit visits. Temperature fluctuations occur every time the door is opened. Publish operating procedures for monitoring and recording temperatures twice a day and instruct personnel to respond to power outages. Contact Thchamber  Laboratory Freezer Manufacturer for details on protecting the contents of laboratory freezers and refrigerators from temperature excursions.

In a medical laboratory, the risk of contamination of cell cultures is immeasurable—no matter how careful the work. Miscalculation of risk is certainly not unheard of, and contamination often results in cultural loss. Therefore, in this blog, we want to shed light on how to systematically detect and avoid contamination in cell lines. Every medical laboratory is under threat day in and day out Microbial contamination in cell cultures—including those purchased from third parties—is not uncommon in laboratories. In fact, the opposite is true: Many cell lines grown in the lab are infected with mycoplasma. Tiny fungal spores lurk everywhere and can be airborne. Of course, when working in a sterile environment, there is room for human error. It's easy to make mistakes. Horror scenarios in cell culture labs - various types of contamination: Microbial contamination (bacteria, mycoplasma, fungi, yeast, etc.) virus contamination Protein contamination (prion) Chemical pollution (leachables and extractables from plastics, heavy metals, etc.) Cross-contamination with other cell cultures Where does pollution come from? 1. How "clean" was primitive culture? Problems usually start with the original material. Even with the best efforts in the production of media, some materials cannot be completely sterile. Therefore, there is always a risk of mycoplasma slipping through the sterile filter. Prions can even survive steam sterilization at 121 °C. 2. Is the working laboratory really a sterile environment? One of the main causes of laboratory contamination is the human body. For example, a lot of cross-contamination can be avoided if laboratory technicians avoid working on multiple production lines at the same time on a sterile bench. One culture can quickly infect another if the fluid is not handled properly. Also, haste is the worst enemy of sterile work. The door of the CO2 incubator should not be left open for no reason, certainly not for long periods of time. Laboratory technicians should only be working on one cell line at a time, no matter how much time pressure they are under. When unpacking single-use pipettes under the bench, once the cap is unscrewed, the cap must be set aside - keyword: Good Laboratory Practice (GLP). For more information, read our blog post: "Five exciting applications for CO2 incubators". 3. Are you using the correct laboratory equipment? Of course, it's entirely possible that even the equipment used in medical labs can lead to contamination of cell cultures. Therefore, we recommend: Use plastic containers without plasticizers Choose the right mold incubator location (locations near the washbasin can lead to soap contamination) Use incubator accessories made of biocide copper When antibiotics are used, antibiotic-free strains should be cultivated from time to time. (This is because antibiotics mask the contamination, and the infection can spread.) What investigative methods can be used to track which infections? The most dangerous thing about mycoplasma infections is that they often go undetected for long periods of time. In principle, contamination events can be controlled and tracked in a variety of ways, some of which are very complex and others less so. Experienced laboratory technicians can tell if cross-contamination has occurred simply by looking through a microscope. If we extract all the DNA from the cell culture, its mycoplasma DNA content can be detected using PCR methods. Laboratories performing viral transduction or bioassays should also check for viral contamination. Laboratories manufacturing drugs for novel treatments should check for bacteria, spores, fungi, mycoplasma, HIV, HCV, and BSE low risk. How should pollution be handled? Every instance of contamination must be recorded and graded. If nothing else, medical labs that hide their contamination problems under the rug are putting their good reputations at risk. Of course, in the event of contamination, special cleaning measures must also be taken: in the case of fungal infections, it is advisable to check whether the laboratory is regularly disinfected with alcohol-based reagents As a general rule, regular spray-disinfection or wipe-disinfection of the interior of the incubator with alcohol-based reagents will help avoid contamination Monthly hot air disinfection is standard medical practice in many laboratories In the case of sensitive stem cells, infected cell lines can only be treated with antibiotics in rare cases. In most cases, the solution is an expensive one - the culture has to be scrapped and the work has to start from scratch. In conclusion: Being able to consistently detect, verify and deal with contamination is an absolute must, especially in medical laboratories that use highly sensitive stem cells and do not use antibiotics. Transparent monitoring is critical. Covering up contamination or letting it spread only increases the danger and is unnecessary. The incubator should always be the safest component throughout the process steps; if a sample is contaminated, in most cases this occurs upstream or downstream of the incubator culture. According to the different range of temperature control, laboratory incubators are applied to different fields. Thchamber have biochemical incubator, widely used for research and production departments such as environmental protection, sanitation and epidemic prevention, agriculture, livestock and aquatic products, drug testing, cell culture, etc.

If you need a incubator lab equipment, you'll undoubtedly be frustrated if it doesn't work. If your device doesn't heat up or cool down at all, or doesn't reach its set temperature, a number of factors could be at play.   In this article, we'll help you troubleshoot by looking at some of the possible causes of temperature problems in your lab incubator, including those that provide refrigeration.   1. There is a mechanical failure If your device doesn't heat up or cool down at all, this can be a serious problem. You may have a damaged component or controller, both of which will require repair and you may need to purchase replacement parts. You might even want to consider buying a new machine.   If your lab incubator is cooling, but not cooling at all, one of the most likely causes is a malfunctioning compressor. In this case, you need to repair or even replace the machine.   2. The temperature protection setting is too low or too high Over-Temperature Protection (OTP) is a handy feature found in many laboratory incubators. It acts as a backup by turning off the heat (and sometimes activating a visual or audible alarm) in case the temperature spikes for some reason. This helps ensure that sample integrity and stability are not compromised by excessive temperature.   Most temperature control devices with this feature use over and under temperature alarms. Predictably, under-temperature protection (UTP) is the exact opposite of OTP. You set a minimum temperature to avoid exposing your samples to excessive cold. If this setting is higher than the set value, your device will not cool to the desired temperature.   3. The temperature needs to be stable In some cases, your machine may appear to be heating up or cooling down, but the temperature on the reference thermometer does not match the primary temperature control reading.   One of the most likely reasons is that the temperature has not stabilized. If the door has recently been opened, the appliance has been turned off, or the temperature has been reset, there may not have been enough time for the internal temperature to stabilize.   4. Not properly calibrated In the above case, if the temperature has had enough time to stabilize, the problem may be with the calibration. If one of the thermometers is not properly calibrated, their readings will simply not match.   It is recommended that the device be calibrated at a temperature similar to your process temperature and every time you change to a new temperature.   5. The door is sealed For incubators and refrigerators, door seals can be an issue if the unit is not reaching temperature. If the seal does not work properly, air exchange will occur between the equipment and the environment, allowing hot air to escape (in the hatching unit) or enter (in the refrigeration unit).   6. Not enough free airflow For these units to work, you really need to make sure there is enough free airflow around the machine. While you don't need a lot of space, it's not a good idea to push the unit against a wall or other equipment. A few inches of "breathing room" on the sides and rear of the unit will help ensure enough free airflow for it to function properly.   For the cooling incubator, if ice forms on the evaporator, the device may not cool sufficiently. This causes insulation and makes it harder for the compressor to do its job. You can remove ice and try to limit door openings to keep moisture from entering the unit.   7. Need more power The power supply is unlikely to be an issue with the machine in an existing setup, but could be an issue in a new installation. If this is the first time you are using the unit or you have moved it to a new location, you should check that the amperage and voltage of the power supply meets the requirements of the unit. You should be able to see these numbers on the machine's nameplate.   Lab Incubator Manufacturer XCH Biomedical have BOD incubator, widely used for research and production departments such as environmental protection, sanitation and epidemic prevention, agriculture, livestock and aquatic products, drug testing, cell culture, etc. ;  The mold incubator is a special constant temperature equipment for water body analysis BOD detection, mold and other microorganism cultivation, widely used for research institutes of health and epidemic prevention, agriculture, livestock and aquatic products;  Heated incubators are used in medical and health, pharmaceutical industry, biochemistry and agricultural science and other scientific research and industrial production departments for bacterial cultivation, fermentation and constant temperature testing. Cooling incubator provides precise temperature control for reliable results in pharmaceutical, industrial testing, food, cosmetics, and microbiological research.