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For decades, Environmental test chamber have been used to study products with countless applications in aerospace, artificial intelligence, automotive, electronics, solar cells, medical, industrial, and consumer research. In these industries, samples or materials to be tested must be exposed to defined changes in environmental factors in order to study their effects and even prepare for future research. Conditions that an environmental test chamber can replicate are: temperature set point (or change), relative humidity or moisture in the form of rain, electromagnetic radiation, vibration, weathering, salt spray, sunlight/UV degradation, and vacuum. The type of testing involved will determine the chamber type; chambers come in a variety of sizes and are designed with different features and options. Environmental test chamber and specimen incubators Prepared samples or materials are placed in the chamber and then subjected to prescribed levels of environmental stimuli to determine their degree of response. The by-products produced are also measured and studied. Environmental test chamber can be used to test products in the following industries: automotive, building materials, chemicals, electronics, wood, cosmetics, plastics, aerospace, metals, pharmaceuticals, tobacco, textiles, packaging industry, biotechnology, biological tissue engineering, ceramics, human and veterinary medicine, food and beverages, microbiology, surface technology, and plant and insect growth. For pharmaceuticals, food and cosmetics, environmental and stability test chamber monitoring is necessary to comply with the rules set by international regulatory bodies. Environmental chambers can measure and control humidity, temperature (e.g. average dynamic temperature), differential pressure, particle counts, lighting and gas levels, and more. Advanced weathering studies in the test chamber help determine safe shelf life levels and use periods. In biology and microbiology, environmental test chambers can be used to monitor the effects of light, humidity and other factors on the growth of plants, algae, viruses, insects and small animals (fruit flies, also known as fruit flies). They are capable of culturing cells, organs and tissues, as well as plant growth and insect feeding. The aerospace industry relies on environmental test chambers to produce vacuums, thermal vacuums, and thermal experiments that simulate conditions in outer space so that space system hardware can withstand extreme stress and climatic conditions. Even astronauts' portable life support systems have been tested using environmental test chamber. Hyperbaric oxygen systems, cryogenic equipment and other instruments are used to test the effects of decompression and altitude conditions. Thchamber, a professional Environmental test Chamber manufacturer. Offering a comprehensive line of Temperature Humidity Test Chamber, thermal test chamber, low temperature test chamber, climate chamber laboratory, high temp high humidity test chamber etc. High precision. Competitive Price. Factory Direct.

Stability studies are typically performed on pharmaceuticals, food and beverages, beauty and cosmetic pharmacy issues and each ingredient to assess how they are affected by external factors such as light, heat, humidity, temperature, pressure, etc. Work to determine how these factors affect the drug. The test helps determine product shelf life and storage guidelines that are critical to consumer safety. Two common stability tests are real-time and accelerated. Live testing is done by storing the drug according to recommended conditions and inspecting or monitoring the product until it fails. Products are tested at 3, 6, 9 and 12 months in the first year, twice a year in the second year, and annually thereafter until the product fails to meet specifications and safety standards. Accelerated research requires storing products in manufacturing environments where different factors such as light or heat are accelerated to determine when a product fails. By performing accelerated studies, degradation can be predicted. XCH-TPS Photostability Test Chamber is equipped with visible light and near-ultraviolet lamp tube, Medicine Stability Chamber can independently control the type of light source, and can print and record visible light illumination and near-ultraviolet radiation in real time. Visible light and near-ultraviolet can be directly set, automatically adjusted and precisely controlled. Containers, closures or other packaging can also be tested for stability. cosmetic Thchamber Labs has received many testing requests from companies and organizations seeking stability testing, as follows: Packaging labs require plastic and polymer testing of HDPE bottles for stack load stability testing and wall thickness testing University research scientists need UK labs to test pharmaceutical compounds during stability tests on standard mouse chow. Food was formulated with this compound to a final concentration of 750 mg of drug per kg of food. To verify and establish formulation stability, we need to measure the drug concentration in the beads over a 6-month period. We need to take an initial measurement (the starting point) and then at least 2 more measurements; at the 3 month point and the 6 month point. Large companies need material labs required for UV stability testing of HDPE: orange HDPE jacket where we have to check the jacket for UV stability and jacket life European Product Safety Laboratories are required to conduct new cream testing for introduction to the EU and international markets, including safety assessment, stability testing, microbial contamination testing, challenge testing, shelf life prediction and any other testing deemed necessary. Cosmetic laboratories are required to conduct cosmetic stability testing and safety assessment testing, including compatibility and challenge testing. Nutraceutical Laboratory requires stability testing of vitamin packs sold as new water formulations. The company is sending products into large chain stores and needs to be tested for stability. See more stability testing requests If you are a product manufacturer or other organization requiring stability testing, please contact the Stability Chamber Manufacturer thchamber or submit an online testing request.

The speed at which vaccines are being developed is unprecedented during the current coronavirus pandemic. Vaccines from companies such as Biontech and Pfizer are already on the market and will be available for vaccination as soon as possible. But how long is the shelf life of a new vaccine? This is exactly what major pharmaceutical companies need to test with Thchamber's constant temperature and humidity chambers today. Typically, it takes ten to twenty years to develop a vaccine. But with the ongoing coronavirus crisis, waiting this long is not a good option. With the number of infections and deaths at consistently high levels, calls for a rapid vaccine delivery are growing. Pharmaceutical companies are struggling to keep up with demand, but are also focusing on analyzing the stability of vaccines, which are developed in years and have to be adjusted based on how the virus mutates. This is where stability testing comes in, for example in the KBF or KBF LQC, a constant temperature and humidity chamber with ICH-compliant light and light control. Smart, safe, economical and reliable: this is Thchamber. One thing is for sure: Thchamber is your reliable partner during the COVID-19 pandemic. Why stress test the new crown vaccine? The goal of pharmaceutical companies is to demonstrate to the public that vaccines are still effective over extended periods of time or after being stored at different temperatures. It's too early to tell how well the various vaccines will work after changing conditions. Constant Temperature and Humidity Chamber: Stability Test of Novel Coronavirus Vaccine Test the effectiveness of the novel coronavirus vaccine using Thchamber's constant temperature and humidity chamber. For this type of test, experts attach great importance to the uniformity of the temperature distribution inside the constant temperature and humidity chamber. Thchamber drying ovens, ultra-low temperature freezers and mildew incubators can also support you during the pandemic. Drying Oven: especially suitable for the disinfection of masks According to the federal government, masks can be reused under certain preconditions. Place the mask in a drying oven at a temperature between 65 and 70 °C for 30 minutes. In this way, the virus can be inactivated. Low temperature refrigerator: can cool down to -25°C Virus samples, such as the new coronavirus, can also be stored in our low temperature freezers. Samples are stored securely in the box and are readily available for additional testing. Incubator: ideal for cell proliferation Large numbers of cells must be grown for the new coronavirus to be tested. Constant Temperature Humidity Chamber: Stability Test of Novel Coronavirus Vaccine Large pharmaceutical companies use Thchamber's constant temperature and humidity chambers around the world to test the effectiveness of the new coronavirus vaccine. For this type of test, experts attach great importance to the uniformity of the temperature distribution inside the constant temperature and humidity chamber.

In a medical laboratory, the risk of contamination of cell cultures is immeasurable—no matter how careful the work. Miscalculation of risk is certainly not unheard of, and contamination often results in cultural loss. Therefore, in this blog, we want to shed light on how to systematically detect and avoid contamination in cell lines. Every medical laboratory is under threat day in and day out Microbial contamination in cell cultures—including those purchased from third parties—is not uncommon in laboratories. In fact, the opposite is true: Many cell lines grown in the lab are infected with mycoplasma. Tiny fungal spores lurk everywhere and can be airborne. Of course, when working in a sterile environment, there is room for human error. It's easy to make mistakes. Horror scenarios in cell culture labs - various types of contamination: Microbial contamination (bacteria, mycoplasma, fungi, yeast, etc.) virus contamination Protein contamination (prion) Chemical pollution (leachables and extractables from plastics, heavy metals, etc.) Cross-contamination with other cell cultures Where does pollution come from? 1. How "clean" was primitive culture? Problems usually start with the original material. Even with the best efforts in the production of media, some materials cannot be completely sterile. Therefore, there is always a risk of mycoplasma slipping through the sterile filter. Prions can even survive steam sterilization at 121 °C. 2. Is the working laboratory really a sterile environment? One of the main causes of laboratory contamination is the human body. For example, a lot of cross-contamination can be avoided if laboratory technicians avoid working on multiple production lines at the same time on a sterile bench. One culture can quickly infect another if the fluid is not handled properly. Also, haste is the worst enemy of sterile work. The door of the CO2 incubator should not be left open for no reason, certainly not for long periods of time. Laboratory technicians should only be working on one cell line at a time, no matter how much time pressure they are under. When unpacking single-use pipettes under the bench, once the cap is unscrewed, the cap must be set aside - keyword: Good Laboratory Practice (GLP). For more information, read our blog post: "Five exciting applications for CO2 incubators". 3. Are you using the correct laboratory equipment? Of course, it's entirely possible that even the equipment used in medical labs can lead to contamination of cell cultures. Therefore, we recommend: Use plastic containers without plasticizers Choose the right mold incubator location (locations near the washbasin can lead to soap contamination) Use incubator accessories made of biocide copper When antibiotics are used, antibiotic-free strains should be cultivated from time to time. (This is because antibiotics mask the contamination, and the infection can spread.) What investigative methods can be used to track which infections? The most dangerous thing about mycoplasma infections is that they often go undetected for long periods of time. In principle, contamination events can be controlled and tracked in a variety of ways, some of which are very complex and others less so. Experienced laboratory technicians can tell if cross-contamination has occurred simply by looking through a microscope. If we extract all the DNA from the cell culture, its mycoplasma DNA content can be detected using PCR methods. Laboratories performing viral transduction or bioassays should also check for viral contamination. Laboratories manufacturing drugs for novel treatments should check for bacteria, spores, fungi, mycoplasma, HIV, HCV, and BSE low risk. How should pollution be handled? Every instance of contamination must be recorded and graded. If nothing else, medical labs that hide their contamination problems under the rug are putting their good reputations at risk. Of course, in the event of contamination, special cleaning measures must also be taken: in the case of fungal infections, it is advisable to check whether the laboratory is regularly disinfected with alcohol-based reagents As a general rule, regular spray-disinfection or wipe-disinfection of the interior of the incubator with alcohol-based reagents will help avoid contamination Monthly hot air disinfection is standard medical practice in many laboratories In the case of sensitive stem cells, infected cell lines can only be treated with antibiotics in rare cases. In most cases, the solution is an expensive one - the culture has to be scrapped and the work has to start from scratch. In conclusion: Being able to consistently detect, verify and deal with contamination is an absolute must, especially in medical laboratories that use highly sensitive stem cells and do not use antibiotics. Transparent monitoring is critical. Covering up contamination or letting it spread only increases the danger and is unnecessary. The incubator should always be the safest component throughout the process steps; if a sample is contaminated, in most cases this occurs upstream or downstream of the incubator culture. According to the different range of temperature control, laboratory incubators are applied to different fields. Thchamber have biochemical incubator, widely used for research and production departments such as environmental protection, sanitation and epidemic prevention, agriculture, livestock and aquatic products, drug testing, cell culture, etc.

Suitable location The placement of vaccine refrigerators is critical. Adequate space is required around medical refrigerators for ventilation. For most vaccine refrigerators, about 30mm of clearance is required on each side of the refrigerator. There are several models of vaccine refrigerators that are designed not to require ventilation gaps at all. It's best to place your refrigerator in an insulated room, rather than against an exterior wall that can get hot and cold with the weather. The size of the location also affects the refrigerator capacity you can install. Appropriate The capacity of vaccine/pharmacy refrigerators needs to be able to safely store vaccines for peak demand, such as pre-flu programs. Overpackaging must be avoided as this can block cold air circulation and put vaccines at risk. For this reason, it is generally advisable to exercise caution and get a slightly larger vaccine refrigerator instead of a slightly smaller one. Vaccine and pharmacy refrigerators are divided into three main capacity ranges: – Under the counter/tabletop vaccine, the capacity of the refrigerator is usually about 130 to 160 liters. – Vertical Pharmaceutical Vaccine Refrigerators typically have a capacity of 350 to 650 liters. – Custom Pharmacy/Pharmaceutical Refrigerator with a capacity of approximately 600 liters and above. External alert If you plan to connect your vaccine refrigerator to your business's alarm system, make sure the vaccine refrigerator allows you to do so. The Thchamber refrigerator is ready for wiring to an external alarm. Thchamber refrigerator must be selected for external alarm. Data logger Consider purchasing a vaccine refrigerator with a data logger. The data logger electronically records temperature readings at set intervals. The stored data can then be downloaded to a computer. Data loggers can be used to audit and establish a record pattern of vaccine refrigerators over time. They're especially handy for determining whether refrigerators over 8 degrees Celsius are doing so within the critical 15 minutes allowed. Alert notification Thchamber refrigerators are now equipped with an alarm system that can send an alert via SMS or email if the temperature inside the refrigerator falls outside the desired range. Thchamber also offers temperature monitoring solutions that can be used with existing vaccines or laboratory refrigerators.

In Stability Testing - Overview, we look at Stability Testing Requirements - Chamber Selection, Validation Requirements, IQOQPQ and IPV Considerations. In order to demonstrate the shelf life of a drug in a certain market, the manufacturer must store it for a specified period of time at the relevant temperature and humidity. This is done in a stabilization chamber, also known as a stabilization cabinet. Regulators in each market, such as the FDA in the US, HPRA in Ireland, specify the temperature and humidity conditions that should be used and the storage time of samples, such as a minimum of 6 to 12 months. During this time, the samples were tested and their potency and degradation were measured and recorded. This is called a stability test. The most common conditions are 25°C/60%RH. For new products, accelerated conditions may be 40°C/75%RH. Other conditions include 30°C/65%RH, 30°C/35%RH and 25°C/40%RH. Another condition is 5°C ±3°C for products intended to be stored in the refrigerator. For products intended to be stored in the refrigerator, test conditions are -20°C ±5°C. Intangible Cultural Heritage ICH, the International Conference on Harmonization of Technical Requirements for the Registration of Medicinal Products for Human Use, develops rules for operational stability testing. ICH Q1A states that conditions should be held constant at ±2°C and ±5%RH during stability testing. Additionally, if these conditions are not met for more than 24 hours, the exam may have to be extended, resulting in a lot of paperwork. If conditions deviate from ±2°C/±5%RH, even for a short time, this should be stated. This may be due to the door opening to "pull" the sample. Such events are usually recorded in the room log. If there is no obvious explanation, it may be necessary to seek help from a service engineer. If the chamber fails, a quick response from the supplier is required, and although he is expected to stock major spares, the auditor also likes the site to stock some. It is also recommended to have redundancy, i.e. have another chamber on site as a backup. The chamber must be fully validated and ready to use. Photostability Test Chamber To demonstrate shelf life under ambient light conditions, samples may be exposed to precise doses of UV and visible light in specially designed chambers. ICH Q1B specifies that temperature should be controlled to prevent localized hot spots. Surveillance and 21 CFR Part 11 Indoor conditions should be independently monitored. This usually requires temperature and humidity transmitters connected to the recording system. In the light stabilization room temperature, UV and visible light intensity will be recorded. The system must comply with US 21 CFR Part 11 regulations, whether it is a paper recorder or a computer system. 21 CFR Part 11 states that all relevant data collection and storage systems must be designed to prevent counterfeiting, corruption, untraceable changes, or data loss. For computer systems, formal testing (IQOQ-Installation Qualification, Operation Qualification) should be performed to demonstrate compliance. Chamber of Commerce Qualification Likewise, formal testing of the new chamber (IQOQ and PQ performance certification) is mandatory. During its lifetime, it should be regularly maintained (usually an annual preventive maintenance service with calibration checks) and preferably mapped with multiple probes per year (IPV - Instrument Performance Verification). PQ and IPV typically require at least one 24-hour monitoring run, unloaded, loaded, or both. During this run, the display conditions must remain at the set point ±2°C, ±5%RH. Test equipment for these tests must be traceable calibrated at least annually and meet the IQOQ standard of 21 CFR P11. Stability Test chamber Selection Considerations The following factors need to be considered: Reliability; is it known, used and trusted? There should be low fluctuations in temperature and humidity capacity; planning for future needs as well as current needs footprint; footprint may be limited Do you offer local service with quick response, spare parts inventory and refrigeration repair certification? The chamber shall have integrated controls including temperature limiters and error message logging It should refill automatically. Low user maintenance Almost no consumables required Sterile moisture is generated. Microorganisms must not be injected into the chamber It should be possible to lock the keyboard There should be an output when an error occurs, which can be monitored by the building management system Should be designed in accordance with GAMP; good automated manufacturing practice IQOQ, PM and IPV have traceable calibration, are 21 CFR Part 11 compliant and should be obtained from the supplier Thchamber.

To understand the importance of humidity testing, just look at a world map. The products that drive our lives need to work in all climates. The phone should also work fine in the dry heat of the Arizona desert and the high humidity of the Atlantic coast. The same goes for life-saving medical equipment, cars, airplanes, and more. Companies environmental test these products under controlled conditions to confirm that they work as designed and to understand where they fail. By doing so, these companies can set expectations for consumers or work to address potential flaws before entering the market. Here's what you need to know about humidity test chambers. Humidity system As the temperature increases, so does the air's ability to hold moisture. This is why temperature and humidity chambers record humidity as a percentage of relative humidity (RH): 5 degrees Celsius of RH is not the same as 20 degrees Celsius of RH. Likewise, the dew point, the temperature at which the air must be cooled for it to condense, must also be taken into account in the test. Over the years, test chamber manufacturers have devised different methods to create wet conditions. Older systems involved misting or water pans. You'll now find atomization more common in salt spray chambers, where a direct and constant water supply is connected to the nozzle. Mist or fog drifts into the work area. On the other hand, immersion pan systems are self-evident. A heater immersed in the water pan slowly produces steam that fills the workspace. However, leading test chamber manufacturers use more modern steam generator systems. The steam generator allows you to precisely control the relative humidity measured by an electronic sensor. They can be sized to fit any chamber and larger workspace. Multiple generators can be used to improve accuracy. The steam generator is an enclosed stainless steel or copper tube. The heating element heats a constant source of water, producing steam or steam. The steam moves to the plenum, mixes with the conditioned air, and enters the workspace with the proper temperature and relative humidity. It is important to pay attention to the quality of the water to make the humidity system last. If the water is rich in minerals, it can cause sediment to build up. If the water is too clean or too pure, it will remove minerals from the metal as it passes through the test chamber. Recommendations vary by manufacturer. For example, Associated Environmental Systems recommends defining ranges for resistivity (0.05MΩ*cm to 6MΩ*cm), conductivity (20µS to 0.167µS), and total dissolved solids (TDS) (10 ppm to 0.083 ppm). Therefore, in addition to the steam generator system, test chambers are often equipped with desalination cylinders to properly condition the water. These (see below), as well as the water itself, should be checked regularly before installing and using the test chamber. Standard humidity chambers have RH ranging from 20% to 95%, but you can customize your chamber to achieve very low or high humidity. A special high humidity sensor allows you to achieve up to 98% RH, while a desiccant air dryer reduces it to 5%. Finally, dry air purification allows you to cycle between extreme humidity conditions. Humidity Chamber Maintenance Regular maintenance is critical to making a test chamber durable, but arguably even more important for a humidity chamber. As important as water is, it can leave problems. Deposits can build up in the steam generator. If left untreated, standing water can lead to the development of mold or mildew. It can also corrode the metal over time. If you notice leaks or other signs of wear, it may be too late for a quick fix. This is why the condition of the water is so important. You should perform an internal water test as part of your quarterly inspection to ensure it is within recommended conditions. If you have a demineralizer, you should check it monthly. When about a quarter of the original color remains, it's time to replace the ink cartridges. You also need to take extra maintenance steps during downtime. You can run your chamber even if you don't test to make sure the system is functioning properly. If you plan to take a long break, wash the outside tank and remove the water from the interior by turning off the water source and opening the drain valve. A repair professional should fix any problems you find as soon as possible, but begin proper maintenance as soon as you purchase your chamber. Discuss with the manufacturer to develop a maintenance schedule that will allow you to test for 10 years or more. Buy a Constant Temperature & Humidity Chamber There is no one-size-fits-all test room. Your testing requirements and the products, equipment and components you plan to test will determine the characteristics of your chamber. This is beyond capability. For example, highly active live loads require larger workspaces indoors so they do not affect specified conditions. The surroundings you are testing with are also important. An experienced manufacturer is required to provide a solution that is right for you. Thchamber builds custom test chambers to meet your specifications. Examples are high humidity sensors and desiccant air dryers. Not to mention, the standard test chamber is equipped to enable remote monitoring and testing. Thchamber provides support and service programs throughout the life cycle of the test chamber. You can test as much as you want with the leading humidity test chamber manufacturers in your team.

Why are humidity chambers or stability chambers used in various industries? They can be used to control humidity in test chambers. Their multifaceted use makes them popular in research settings. Here are ten reasons why a constant temperature and humidity chamber is useful. Humidity test chambers can be used to detect the effects of predefined environments, electronic components, industrial and biological materials. They can spot even the tiniest flaw in a product. Therefore, it is widely used in high-precision applications such as medicine and chemical industry. The humidity chamber is capable of detecting temperature and humidity ranges. Since the entire life cycle of a product depends on the accuracy of that chamber, the company makes them very precise. This chamber can be used to study cells in living organisms. The better the accuracy during the study; the more accurate the results. A high precision chamber does the job well. There is no better way to provide the optimum conditions needed to test vegetable and plant productivity. High-quality temperature and humidity test chambers can be applied to all types of test environments. Genetic research, pharmaceutical research, and academic research are fields that require a controlled environment during experimentation. Therefore, they require stability chambers or humidity chambers. Because they are connected to high-performance microprocessor-based systems; very high precision is achieved. Automatic data logging and collection is just a few clicks away in the smart room. These laboratories provide a stable temperature range and humidity controlled environment. Excellent humidity chamber function, better control system, worry-free operation and user-friendliness are their characteristics. The stability test chamber has a flexible design. They comply with international quality guidelines and validation protocols. Since most chambers offer on-site verification services, maintaining the accuracy of the results is not a daunting task. The modern room is stylish, beautifully designed and functional. Therefore, they serve consistently and accurately year after year. Despite modern features like Ethernet monitoring and control, stainless steel body and indoor lights, humidity chambers in India are still affordable. There are many competitive products now. Buyers can choose the one that best meets their needs. Thchamber offers humidity chambers with features and functionality to meet most application needs. However, if required, custom products can be developed according to user specifications.

Why Lab Refrigerator Temperature Alarms Are Crucial What could go wrong? Perhaps the first thing that comes to mind is a power failure. If your facility does not have emergency generators that come online immediately, you need a backup plan to quickly move production to a backup refrigeration system. Less likely, but not unknown, is a mechanical failure in the refrigeration system or a temperature excursion due to poor maintenance, such as icing on the evaporator coil. Another example is accidentally leaving the unit's door ajar. As a final example in this post, a temperature monitor that activates an alarm can fail. For whatever reason, personnel must be alerted if the temperature is above or below the set value. Quick response to temperature excursions helps protect contents from spoilage or loss of potency. Temperature alarm system To understand the alarm system, we first set up the stage. Temperature alarms are programmed by personnel based on the proper storage temperature of materials in freezers and refrigerators. Use a mechanical or digital thermostat to set the temperature. Temperature monitors consist of probes placed in refrigerators and freezers and connected to onboard or external display and control devices. Many of these come with battery backup to maintain functionality in the event of a power failure. For more information on temperature controls and monitors, see our post on the topic of vaccine storage. On-board alarm Examples of on-board systems include Nor-Lake Scientific laboratory freezers and refrigerators available from Tovatech. These feature digital LED microprocessor temperature controllers with high/low visual and audible temperature alarms and remote alarm contacts to alert personnel elsewhere in the facility. A temperature sensor is placed in the bottle filled with glycerin to better reflect the temperature of the contents than the ambient temperature in the unit. Such an arrangement also reduces the chance of triggering an alarm when the unit door is opened. Some models of Scientific Refrigeration systems provide power failure alarms and door ajar alarms. Auxiliary or optional alarm system General purpose laboratory refrigerators and freezers can be equipped with an optional digital thermometer alarm consisting of an internal probe housed in a glycerin-filled bottle that is wired to external control and alarm devices. Probably the best solution for notifying refrigeration failures is the iLab 600 temperature monitoring system from Tovatech. The device operates independently of the device by collecting data from an internal probe connected through an access port to an external pod, which in turn is connected to the facility's LAN. The iLab 600 has two functions: A sophisticated programmable high/low temperature alarm that sounds locally and sends email, text, phone or pager alerts to the personnel list during off hours. It also captures, remotely stores and instantly retrieves compliance data reports on laboratory freezer and laboratory refrigerator performance. An optional USB temperature data logger with built-in alarm can be used to automatically record internal temperature at user-programmable intervals using a NIST traceable probe. To read the results, simply plug the USB flash drive into the computer and transfer the data to the PC for viewing and archiving. In addition to the onboard and optional digital thermometer alarms, an iLab 600 or USB data logger is recommended for two reasons. First, you shouldn't rely on a single temperature sensor to drive a temperature warning system. There should be at least two completely separate monitoring systems with alarms linked to separate temperature sensors. Second, they provide a way to acquire, store and retrieve stored temperature data based on good laboratory and good manufacturing processes. Other Pharmaceutical Refrigerator Tips Despite sophisticated temperature monitoring and alarm systems, laboratory personnel have a responsibility to protect the contents of refrigerators and freezers from spoilage due to improper storage temperatures.   Be prepared for prolonged power outages. Large facilities should have a backup emergency power system to keep refrigerators and freezers functioning properly. Smaller labs can use portable generators. If they shouldn't have procedures in place to quickly move valuable specimens, vaccines and medicines to off-site locations. Keep in mind that full freezers and refrigerators will keep the temperature longer. Fill the empty space with an ice pack or water bottle. Minimize unit visits. Temperature fluctuations occur every time the door is opened. Publish operating procedures for monitoring and recording temperatures twice a day and instruct personnel to respond to power outages. Contact Thchamber  Laboratory Freezer Manufacturer for details on protecting the contents of laboratory freezers and refrigerators from temperature excursions.

A Precision Lab Incubator Equipment from china Laboratory Incubator Manufacturer is an important piece of equipment in any laboratory, but reliable results require the proper use and maintenance of your equipment. What's more, some models can get quite expensive, and you may not want to replace your machine as often. 1. Position your device correctly Proper placement of your equipment ensures that it operates efficiently and minimizes exposure to potential contaminants. When choosing the best location for your laboratory incubator, you need to consider the following factors: Doors and vents can blow in pollutants and increase the chance of fungal growth. What's more, they create airflow that affects the temperature stability of the device. Direct sunlight can cause temperature fluctuations and problems with the anti-condensation feature. You need enough space (at least three inches) around the device so that heat can escape and power cords and outlets are easily accessible. Place floor-standing incubators on shelves to reduce the risk of influx of contaminants when the door is open. Avoid damp, damp areas where fungus can grow. Place the device away from sources of vibration, such as shakers, blenders, or refrigerators, as vibration can affect cell growth. Make sure the area around the device is as clean as possible. The ideal conditions for a laboratory incubator are a temperature-controlled environment and clean room conditions. Since this is usually neither practical nor feasible, considering the above factors is sufficient for most applications. 2. Monitor the temperature The thchamber heating incubator is typically maintained at 37°C for optimal growth of cell cultures. Temperature deviations can inhibit growth or even destroy cultures. A temperature sensor is included in the unit, but how do you know you can always rely on your sensor? One way to ensure the correct temperature is to use a second thermometer. If your incubator has a glass door, you can install a calibrated thermometer inside the glass and read it without opening the door. You can check this against the sensor temperature and if they are different you know the sensor needs to be recalibrated. Avoiding opening and closing doors unnecessarily helps keep the temperature stable (and prevents contaminants from entering the chamber). If you are concerned about the incubator door being opened unintentionally, you can choose a unit with a door lock. 3. Monitor humidity and carbon dioxide Optimal growth conditions for cell cultures also include specific humidity levels and, in some cases, CO2 levels. Tissues and cells are sensitive to changes in these parameters and therefore require close monitoring. If the humidity is too low, your cell culture medium may evaporate, or your growth medium may become too concentrated. The ideal humidity is usually around 95%, to keep it at this level you need to ensure that the water pan (under the incubator) is never at risk of drying out. For CO2 incubators, you need to monitor CO2 levels. This is usually kept at 5% to maintain a constant pH for optimal growth. The CO2 sensor helps by indicating when and how much CO2 needs to be added to the chamber. You can check CO2 levels every few months with an external gas analyzer. 4. Regular temperature calibration We discussed monitoring temperature above, but thermometers should also be regularly verified and calibrated. The exact timeline will depend on your application, but each month is a good guide. The unit should also be recalibrated if verification determines that the unit is required and after an abnormal event such as a power outage or spill cleanup. For reproducible results, calibration should be performed at normal operating temperatures. For incubators used in critical or sensitive experiments, you should also consider arranging for annual calibration by an external facility.

With the advent of the COVID-19 epidemic in 2020, human beings have to coexist with the new coronavirus. It's time for healthcare facilities to pay close attention to their refrigeration equipment for vaccine storage and temperature monitoring. This article summarizes their advice on how to store Covid-19 vaccines safely. How to Choose a Vaccine Refrigerator for Safe Vaccine Storage Vaccine storage temperature is determined by the manufacturer. Typically, most refrigerated vaccines must be stored between 2⁰ and 8⁰C. Frozen vaccines should be stored between -50⁰ and -15⁰C. The first guideline for VFC-compliant vaccine storage is that the refrigeration system does not allow temperatures above or below recommended storage temperatures. Set your refrigerator or freezer thermostat to the factory setting or midpoint temperature, which will reduce the chance of temperature excursions. That's because over the years, when refrigerators used to store vaccines fail to keep vaccines at recommended temperatures, huge financial losses can occur. These temperature excursions can cause vaccines to lose efficacy. In addition to the financial loss, there is the inconvenience of calling patients back for re-vaccination without compromise. For example, Carmen Heredia Rodriguez of Kaiser Health News published an article in February 2019 titled "Vaccines are sometimes stored improperly, reducing their effectiveness." This article covers temperature control events in California and Indiana. The most important thing to store vaccines is to use separate vaccine refrigerators and freezers. That's because they hold the desired temperature better than a combination refrigerator/freezer. The exception is a combination vaccine refrigerator and freezer if each compartment has its own compressor, thermostat and exterior door. The organization notes that stand-alone units can range in size from pharmaceutical-grade compact, above- or below-counter units to full-size units. Home refrigerators are not recommended under any circumstances. The CDC even said that such devices are prohibited from being used to store VFCs or other vaccines purchased with public funds. Vaccine Storage Tips Regardless of the capacity of your vaccine refrigerator or freezer, there are a few "must dos" to keep in mind: A full unit will hold the temperature better, but don't overfill. Leave room for air circulation. Replace the removed refrigerator stock with a pre-chilled water bottle. Replace the removed freezer with a chilled water bottle. Allow space for circulation between containers and keep contents 2-3 inches from the walls and back of the unit. Post notes that food and beverages have no place in the vaccine storage unit. Keep contents in original packaging with expiry date up front. If your unit has door racks, fill them with frozen or frozen water bottles, not vaccines. Vaccine temperature is better. Designate a person to perform this task. It also provides an opportunity to monitor vaccine stocks. Contact the scientists at China Medical Refrigerator Manufacturer thchamber to learn more about choosing the right vaccine refrigerator equipment for your practice.

Believe it or not, most of the technologies we take for granted today would not be possible without an environmental test chamber. At the heart of research and development, environmental test chambers are used to determine product performance, reliability, strength and failure points in many industries. Today, environmental test chambers vary in performance, size and capability. They are critical to a wide range of industries, from small handheld devices to electric vehicles. The first formal environmental laboratory was not invented until 1951 by Charles Conrad. He does this by altering his home refrigerator to achieve extremely cold temperatures as low as -125°F. New environmental testing techniques take off from there. With the expansion and formalization of environmental testing, special types of temperature, humidity, corrosion, vibration and other test chambers began to appear. Below are some common types of environmental test chambers today, ranging in size from small benchtop models to walk-in or drive-through rooms. Temperature and humidity chamber Using a precisely calibrated heating and cooling system, the  temperature and humidity chamber must maintain precise control of the test environment. The fast rate of change simulates the weather conditions a product may encounter during its life cycle, while maximizing test time for efficiency. Today, you can expect temperature accuracy to within ±0.5°C and relative humidity (RH) accuracy to within ±2%. The constant temperature and humidity chamber can be used for drug stability testing, battery testing, temperature cycling, solar testing, stress screening, HALT and HASS testing, etc. Industry leading temperature and humidity chambers capable of -70°C to +180°C (-94°F to 356°F) range and produce standard RH ranges between 20% and 95%. Using a high humidity sensor, some chambers can reach 98% RH or as low as 5% RH desiccant air dryers. Laboratory oven Commonly used for aging, baking, curing, drying and sterilization, laboratory ovens and liquid cooling ovens are also used for R&D, product design and testing. Test chambers have grown stronger over the past few decades and have continued to evolve over time. For example, Thchamber can remotely monitor ongoing tests. Manufacturers are also keeping pace with the growing importance of battery testing. They designed fixtures that fit in the test chamber to accommodate test batteries for everything from battery fonts to medical devices, drones, electric vehicles, and more. Most of our technological advancements are as good as our environmental testing techniques, which help explain the explosion of innovation and new technologies we've seen over the past 80 years. It is exciting to imagine what will happen to environmental testing technology in another half century.